Fig. 2

Proportion of swollen joints at individual locations of the 28-joint count at follow-up visits after start of treatment with the first tumour necrosis factor inhibitor (TNFi) in joints that were swollen at baseline (BL). The proportions were calculated in relation to the total number of joints assessed at 6, 12, 18, and 24 months. A Joints located along a proximal–distal axis of the upper extremity and the knee. B Joints positioned along an anterior–posterior axis of the hand (digits 1–5). Metacarpophalangeal and proximal interphalangeal joints of each digit were combined for analysis