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Table 2 Rate of resolution of swollen joints after start of TNFi in pairwise comparisons of joints (subgroups of patients affected at both sites)

From: Differences in the response to TNF inhibitors at distinct joint locations in patients with psoriatic arthritis: results from nine European registries

 

Site of joint

Number of affected joints/patients

Reference joint(s)

HR (95% CI)

Proximal–distal axis of upper limb

Shoulder

(74/56)

MCP3/PIP3

3.27 (1.27; 8.42)

Elbow

(99/78)

MCP3/PIP3

3.89 (1.80; 8.40)

Wrist

(537/338)

MCP3/PIP3

0.75 (0.63; 0.90)

Anterior–posterior axis of the hand (digits 1–5)

MCP1/PIP1

(490/264)

MCP3/PIP3

1.43 (1.14; 1.79)

MCP2/PIP2

(1107/539)

MCP3/PIP3

1.24 (1.05; 1.46)

MCP4/PIP4

(650/352)

MCP3/PIP3

2.01 (1.65; 2.44)

MCP5/PIP5

(431/247)

MCP3/PIP3

2.33 (1.83; 2.96)

Knee vs. elbow

Knee

(103/75)

Elbow

0.55 (0.27; 1.10)

  1. Estimates of resolution rates (HR and 95% CI) from individual interval-censored mixed-effects Cox proportional hazards models. Confounding is minimized since patient characteristics are equally distributed for both joint sites in each comparison