Fig. 1

Gene expression profiling of LN biopsies from IA patients and healthy individuals Volcano plots depicting differentially expressed genes of ACPA + RA (A) and ACPA- IA (B) compared to HCs. Cut of values of p = 0.05 and log2-foldchange = 0.5 are represented by red lines. Healthy control (HC), anti-cyclic citrullinated protein antibodies (ACPA), rheumatoid arthritis (RA), inflammatory arthritis (IA)